Equipment Processing Report by PharmTech logo
January 2013  
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Production Lines

Using Micronization to Reduce API Particle Size
Micronization can be performed with a jet mill or bead mill.

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In The Mixer
Improving Tablet-Press Tooling Maintenance and Storage
Adopting a seven-step process resolves tableting problems

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Troubleshooting Editor's Picks

Logging the Cold Chain
Advances in data loggers and radio-frequency identification tags help meet the increasing need for managing the pharmaceutical cold chain

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Editor's Pick product

Editor's Pick product

The Shuttle Portable Ultra-Low Temperature Freezer from Cole-Parmer offers secure, low-temperature transport.
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Editor's Pick product

The RotaMass LR dual bent-tube coriolis meter from Yokogawa measures liquid and gas flow at low rates.
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>>Coming Soon: An extended article on tablet-press tooling maintenance from I Holland in the February issue of Pharmaceutical Technology.

Showcase (Sponsored)
 
Fette Compacting America Inc

Fette Compacting now offers the FE55, a tablet press that delivers unprecedented levels of productivity, flexibility and availability. The FE55 is clad in easily-detachable, FDA-certified high-performance polymer panels and offers 360-degree access. The FE55 has the ability to produce single- and double-layer tablets and direct pressing – the only machine of its compact size to offer all three capabilities. Click here for more info.
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Ropack

Ropack provides solid dose packaging services to leading pharmaceutical and healthcare companies. Operating in 250,000 square feet, Ropack offers stick-pack production in a 15,000-square-foot state-of-the-art facility, equipped for production and packaging of humidity- and temperature-sensitive products. Other Ropack services include blister, bottle and pouch, powder blending and encapsulation and in-country clinical trial packaging and distribution management. Ropack has ample capacity, technology and resources. paul.dupont@ropack.com
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Product Announcements
  • Endress+Hauser's Liquiphant FailSafe level switches for pump and overfill protection use internal redundancy to offer functional safety within one device.
  • Rockwell Automation extended the ratings of its Allen-Bradley PowerFlex 755 AC drives to 1500 kW/2000 Hp to allow a wider range of high-power applications.
  • EMD Millipore's Mobius FlexReady Solution with Smart Flexware Assemblies for tangential flow filtration is a fully automated single-use system.
  • Sartorius Stedim Biotech’s Sartoguard NF prefilters feature a unique combination of high performance polyethersulfone membranes and innovative nanofleece technology for liquid prefiltration applications in biopharmaceutical manufacturing.
  • Mauser Group’s L-Ring Drum H-Care is a tight-head drum designed to meet high requirements for regulatory conformity of packaging materials.

Calendar of Events
  • Feb. 13–14: Pharmapack Europe (Paris) features an exhibition, technical workshops, and presentations reviewing trends and advances that improve benefits to patients.
  • Feb. 25–26: ISPE’s Critical Utilities Education Intensive (Tampa, FL) offers relevant case studies to illustrate alternatives for cost-effective, risk-based approaches to design, construction, and maintenance for critical utilities.
  • Mar. 4–5: ISPE’s Aseptic Conference (Baltimore, MD) presents the latest in aseptic processes, including barrier isolation and containment technologies, cleaning and sterilization, and disposables.
  • Mar. 11–14: At DCAT Week 2013 (New York, NY), the Drug, Chemical & Associated Technologies Association (DCAT) organizes strategy sessions, education programs, and networking events.
  • Mar. 17–21: Pittcon (Philadelphia, PA) is the world’s largest annual conference and exhibition on laboratory science.
PharmTech Poll: Regulatory Enforcement

What area do you think will see increased regulatory attention and enforcement in 2013?

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