The Rise of In-Line Blending
Growing interest in continuous drug manufacturing has brought greater attention to in-line blending, a process that the petroleum and fine-chemicals industries have used for decades.

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In-House Nitrogen Generation Can Enhance Safety and Decrease Costs
Many facilities buy compressed gas tanks or evaporate liquid nitrogen to supply processes with dry, high-purity nitrogen. An in-house nitrogen generator, however, provides several significant benefits.
>>Coming Soon: Find out how close the pharmaceutical industry is to having a fully automated, continuous manufacturing line at Pharmaceutical Technology’s “Challenges of Continuous Processing” session at 1:30 pm on March 29 at INTERPHEX 2011.
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ASSMANN SMALL DOUBLE WALL TANKS
Small double wall tanks, 20 to 405 gallons, provide primary/secondary containment for hazardous and corrosive chemicals Assmann Corporation of America.
http://www.assmann-usa.com/Double_Wall_Tanks.htm
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Bosch
Click
to learn more about the most advanced capsule filling systems available. Mit freundlichen Grüßen / Best regards
Tony Miller
PANP/MKT
Tel. 763-493-6756
Fax 763-493-6776
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GelJacket™ CO2 Incubator
Caron’s new 10 cu. ft. GelJacket Benchtop IR-CO2 Incubator is the most innovative technological advancement for cell culture incubators in decades. GelJacket is active gel insulation, located in every incubator wall. GelJacket has thermal advantages far surpassing any other CO2 incubator. Units come standard with an IR sensor, controlled humidity, decontamination cycle and more! To learn more visit
www.caronproducts.com/geljacket
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RoTab T R & D Tablet Press The portable RoTab T offers precise scale-up to free up production machines from trials. The cGMP design enables easy validation for the production of small tablet batches and pre-clinical studies.
- automatic tablet weight regulation via filling depth
- seamless RPM adjustment for die table and Optifiller
- servo-driven compression roll stations
- optional servo-driven tablet hardness adjustment
- automatic punch lubrication with adjustable intervals
http://www.fette-compacting.com/next
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Spirax Sarco Presents a Solution for the Prevention of Reverse Flow and Cross Contamination
http://www.spiraxsarco.com/us/about/news-article.asp?news_id=48
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Delivering Process-Scale Performance and Enabling True Linear Scale Up at Pilot Scale
Pall’s PKP chromatography systems, easy–to-use software and flexible component combinations, along with precision instrumentation, enables systems that encompass a flow range of 1 to 150 L/h, for optimum gradient performance and true linear scale-up in a compact footprint.
http://www.pall.com/biopharm_54155.asp
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Custom Metallic Filtration Products for Prototypes and Small Runs
W. S. Tyler specializes in design, service, consultation and fabrication of custom metallic filters for prototyping and small production needs. These products are constructed in stainless steel, Hastelloy, and other metallic filter mesh and/or metal sintered laminates. They allow migration-free filtration from 1 to 200 micron.
The filter grade woven wire cloth is available in several twill designs to meet specific filtration application requirements.
Pharmaceutical applications include pressure and vacuum filters, filter candles, Nutsche filters, CIP filters, and fluidized bed dryers. Visit us at Interfex, booth 2057 W.S. Tyler
http://www.wstyler.com/html/engineered_prod.html
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Biocontainer "Standards Guide"@ www.meissner.com
Meissner's repository of ready-to-use single-use TepoFlex® biocontainer assembly designs can be downloaded from Meissner.com. These "standards" can be purchased for 3-4 week delivery, or used as the basis to streamline the design process for customized assemblies. Configurations include 2D end-ported, 2D face-ported and 3D configurations
www.meissner.com
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- Biotage offers 750-g and 1500-g cartridges for reverse-phase chromatography and optimized silica for the separation of amines.
- Emerson Process Management’s Micro Motion Filling Mass Transmitter with a Micro Motion Coriolis sensor is suited for various linear and rotary filling machines in the life-sciences industry.
- Grieve’s No. 796 electrically-heated Class 100 cleanroom cabinet oven dries water from stainless-steel and PTFE filter assemblies.
- The VariMax IFRG indirect-fired gas heater from Munters heats process airstreams without contaminating the air with the products of combustion.
- National Bulk Equipment’s fully automated, self-contained, bulk-material mixing system blends five highly caustic, free-flowing powdered additives with a poorly flowing, high dusting base ingredient.
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- Mar. 23–25: Pharma Packaging and Labeling Compliance Conference (Barcelona). At this event, pharmaceutical packaging specialists from around the world will share their perspectives, which will influence pharmaceutical packaging and labeling in 2011.
- Mar. 28–30: IVT’s 2nd Annual Validation Week EU (Amsterdam). This three-day conference and exhibition will unite industry experts with experience in all facets of the validation arena, including process validation, computer and software validation, method validation, cleaning validation, and facility qualification.
- Mar. 29–31: Pharma and Biotech Supply Chain World Asia (Singapore). At this event, pharmaceutical companies, biotech companies, API suppliers, and leading solution providers will discuss strategies for achieving an efficient, reliable, and cost-effective supply chain.
- Mar. 29–31: INTERPHEX 2011 (New York). Attendees will see the newest products and equipment, view live demonstrations, network, get expert advice about specific challenges, find resources and source new products, and learn about emerging or changing trends.
- Apr. 4–6: WHCC 8th Annual Pharmaceutical, Biotech and Medical Device Summit (Washington, DC). CEOs and senior executives will focus on creating strategies to demonstrate clinical and cost effectiveness, evidence-based and personalized medicine, and the implications of healthcare reform, comparative effectiveness, and reimbursement changes.
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