Current Trends in Mass Spectrometry e-newsletter:
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October 26, 2016
Presented by LCGC and Spectroscopy
 
Featured Articles
Quantitation of Albumin and Creatinine in Urine by MALDI-TOF Mass Spectrometry
This MS-based method represents a simple, fast, and attractive alternative to current immunoassay-based methods for the quantitation of albumin and creatinine in urine. This protocol enables the direct detection and measurement of the intact analytes from the same sample preparation, requiring only a 10-fold dilution of a urine sample into a MALDI-TOF matrix solution.
Refurbished Mass Spectrometry Solutions for the Clinical Lab
The adoption of mass spectrometry in the clinical laboratory remains on the rise. IET offers high-performing instruments that deliver speed and sensitivity to help solve complex analytical problems faced by clinical chemists. Learn about refurbished clinical mass spectrometers here
A Fast Method for Targeted Allergen Screening and Nontargeted Characterization for Personal Care Products
A gas chromatography–time-of-flight mass spectrometry method was developed to screen for and quantify regulated allergens in approximately 5 min. This method used a short and narrow chromatographic column along with mathematical deconvolution of the TOF-MS data to separate the target allergens from each other in the standards and from matrix interference in samples.
Application note
Detection of pesticides by miniature mass spectrometer
BaySpec's newly developed Portability™ is the only transportable mass spectrometer using linear ion trap. It comes with multi-interface support allowing ambient and low pressure sampling. Read more
Comprehensive Fragrance Profiling of Ginger, Wintergreen, and Rosemary Essential Oils by GC–TOF-MS with Soft Electron Ionization
This study demonstrates that GC–TOF-MS can be a useful approach to generate comprehensive fragrance profiles of essential oils. Peak deconvolution enables discrimination between closely eluted compounds, and soft electron ionization, assisted by comparison of ion ratios, makes it possible to discriminate between isomeric monoterpenes with very similar mass spectra at conventional 70-eV ionization energies.
Application note
Switch from Helium to Hydrogen
Helium is becoming increasingly expensive. Today, lab managers choose to switch to hydrogen, an inexpensive and reliable gas source. Read more
Nontargeted Metabolite Profiling in Next-Generation Plant Breeding: A Case Study in Malting Barley
The power of nontargeted metabolite profiling is illustrated in a study focused on the determination of molecular markers in malting barley that are predictive of desirable malting quality for brewing applications. The metabolite extraction, detection, and analysis methods are high-throughput and reproducible, and therefore, this approach represents a practical addition to the plant breeder’s molecular toolbox.
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