Featured Articles

High-Throughput Experimentation: Where Does Mass Spectrometry Fit?

In the pharmaceutical industry, the use of mass spectrometry in high-throughput experimentation (HTE) has increased, thanks to the technique's speed, sensitivity, and selectivity. We systematically evaluate the applicability of multiple MS techniques for different types of HTE samples and purposes, reviewing the pros and cons, and provide practical recommendations, Illustrated by application case studies. read more

Laser Thermal Desorption and GCxGC for Harsh Environment and Planetary Mass Spectrometry

The development of analytical instrumentation for harsh terrestrial environments and outer planet space exploration exponentially increases instrument requirements—for features such as robustness, autonomous operation, and speed—and poses unique system integration challenges. Here, we explore the use of laser thermal desorption coupled to comprehensive two-dimensional gas chromatography (LTD-GCxGC) for use with a compact, high-resolution mass spectrometer for challenging applications. read more