Experimental investigation of scale effects in high throughput process development studies
High throughput process development (HTPD) has already been proven successful, mainly because it allows for faster investigation of larger experimental space of process conditions, with smaller sample consumption. In general, HTPD studies to develop chromatography steps can be performed using different miniaturized formats that support parallel experimentation. In this work we have analyzed effects related to local hydrodynamic conditions around Protein A medium particles.
Review poster |