Tangential flow filtration (TFF) is often the technique of choice for fast, efficient concentration and buffer exchange for biomolecules. But, how do you choose the right single-use filter and process setup for TFF? In this interview with BioPharm International, Mike Dango, product manager for hollow fiber filtration products at GE Healthcare, provides guidance on this important issue as well as tips on designing an optimal fluid path. In addition, Dango covers applications that may benefit from a single-use TFF process and offers insights on how to minimize bioburden risk.