This presentation reviews for the attendee numerous quantitation techniques available when analyzing samples by GCMS triple quadrupole technology. At the end of the presentation the attendee should be able to better identify which method of quantitation is most appropriate for their applications, better understand the advantages of each quantitative method, and learn how matrix can drive selection of the most appropriate quantitation method. Each attendee will also learn how selectivity and sensitivity are directly related and what the impact can be when focusing on one versus the other.