Register Free at
http:// www.chromatographyonline.com/proteomics
Event
Overview:
LC-MS is a key enabling technology in the field of proteomics and new developments in this area are providing tools to help researchers obtain greater amounts of useful proteomics data. This presentation will introduce PRIME (PRoteomics with Integrated Maldi and Electrospray) as a multi-tier approach to decipher biology and disease and to turn proteomics data into knowledge.
This presentation will explore the integration of proteomics LC-MS applications with a range of new tools for sample preparation, separation, detection, and data analysis to help solve complex proteomics problems. These tools include nano-capillary UHPLC, CaptiveSpray Ionization (CSI), MALDI, High Resolution MS, CID/ ETD Detection and the ProteinScape software suite.
For comprehensive proteomics, nano-UHPLC coupled on-line with CSI-MS or off-line with a MALDI-MS, integrated with automated data analysis, can provide identification and characterization of thousands of proteins present in complex samples in a few hours. In functional proteomics, these tools, coupled with ETD detection, are used to identify, characterize, and quantify post-translational modifications (phosphorylation, glycosylation, etc.) that play important roles in systems biology. For targeted proteomics, cap-UHPLC coupled with CSI-MS can be utilized for high throughput screening and quantification of potential protein biomarkers in clinically relevant samples.
| Key
Learning Objectives: |
Specifically, this webcast
will briefly describe the:
- A better understanding of the application of nano-capillary UHPLC for the separation of proteins and peptides prior to MS detection
- The integration of LC and MS using CaptiveSpray Ionization to provide the sensitivity, throughput, and robustness required for next generation proteomics
- Utilization of the PRIME approach to proteomics LC-MS for a better understanding of how proteomics data can be translated into biological knowledge
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| Who Should
Attend: |
- Scientists and managers in academia, pharmaceutical, biotech and clinical laboratories involved in the isolation, identification, characterization and/or quantification of proteins and peptides
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| Presenters: |
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Kerry Nugent
Senior Vice President – Liquid Chromatography
Long Bio
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| Moderator: |
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Laura Bush
Editorial Director
LCGC |
For
questions, contact Kristen Farrell at kfarrell@advanstar.com |
