OCTOBER 2012
Translating GC Methods from Helium to Hydrogen Carrier Gas

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CHROMacademy presents a definitive guide in translating your GC methods for use with Hydrogen Carrier. The impact of global Helium supply issues on Gas Chromatography methods is studied and the use of hydrogen as an alternative carrier gas is considered. A balanced discussion on Hydrogen safety is presented, alongside method translation, including all of the important method and instrument parameters to ensure retention, selectivity and resolution are maintained. The use and limitations of hydrogen carrier with mass spectrometric detectors is also discussed.
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Key Learning Objectives
Have a balanced discussion on the safety implications of using hydrogen for GC
Learn about the physical and chromatographic differences between helium and hydrogen as carriers
Understand how to successfully translate methods so that retention, selectivity and resolution are preserved or enhanced
Learn how to ensure that selectivity differences are minimized when transferring gradient temperature programmed methods
Understand the implications of using hydrogen on FID detector performance
Appreciate the considerations and limitations of using hydrogen as a carrier for GC-MS instrumentation

Also Included in This Tutorial
Related Articles from LCGC
Method translation in Gas Chromatography
Hydrogen carrier gas and vacuum compensation
Frequently asked questions about Hydrogen carrier gas
Using Computerized Pneumatics – 2 part article
Flow, pressure and temperature calibration
CHROMacademy GC E-Learning Modules
GC Temperature Programming
Sample Introduction

GC Detectors

CHROMacademy Webcasts / Essential Guides
Developing fast capillary GC methods

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Joe Furrevig, Editor contact




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