JUNE 2012
Troubleshooting GC Separations Part 1
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In this tutorial with accompanies the Essential Guide Webcast (see opposite), Dr. John Hinshaw (Senior Scientist , BPL Global Ltd) and Tony Taylor (Technical Director, Crawford Scientific), present practical troubleshooting tips for GC separations, with special emphasis on retention time variability, loss of efficiency and poor peak shape. The session includes a wealth of practical information on GC separation issues and all our real world problems are related to both separation chemistry and hardware issues. A ‘must read’ for everyone working with GC instruments
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Key Learning Objectives
Learn how to quickly identify separation problems in GC
Investigate causes of retention time variability and how to fix and prevent issues with carrier gas flow rate reproducibility and injection acquisition parameters
Highlight major causes of peak shape deformation, including peak tailing caused by activity within the system and key preventative measures to minimize secondary retention and maximize sensitivity / peak area reproducibility
Investigate the reasons for efficiency loss in GC and develop strategies to prolong column lifetime and maximize system efficiency
Develop curative and preventative maintenance operations to optimize GC separation quality

Also Included in This Tutorial
Related Articles from LCGC Magazine
When Peaks Collide – 3 part article
Spring Cleaning
Extreme Leaks
Pinning down tailing peaks – 2 part article
Using Computerized Pneumatics – 2 part article
CHROMacademy GC E-Learning Modules
GC Temperature Programming
Sample Introduction
GC Detectors
CHROMacademy Webcasts / Essential Guides Tools
GC Troubleshooting - Gas Supply and Inlet Issues
GC Troubleshooting – Column and Detector Issues
Column Choice for Capillary GC

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