OCTOBER 2012

Translating GC Methods from Helium to Hydrogen Carrier Gas



CHROMacademy presents a definitive guide in translating your GC methods for use with Hydrogen Carrier. The impact of global Helium supply issues on Gas Chromatography methods is studied and the use of hydrogen as an alternative carrier gas is considered. A balanced discussion on Hydrogen safety is presented, alongside method translation, including all of the important method and instrument parameters to ensure retention, selectivity and resolution are maintained. The use and limitations of hydrogen carrier with mass spectrometric detectors is also discussed.

KEY LEARNING OBJECTIVES
•	Have a balanced discussion on the safety implications of using hydrogen for GC
•	Learn about the physical and chromatographic differences between helium and hydrogen as carriers
•	Understand how to successfully translate methods so that retention, selectivity and resolution are preserved or enhanced
•	Learn how to ensure that selectivity differences are minimized when transferring gradient temperature programmed methods
•	Understand the implications of using hydrogen on FID detector performance
•	Appreciate the considerations and limitations of using hydrogen as a carrier for GC-MS instrumentation

ALSO INCLUDED IN THIS TUTORIAL