19 June 2014 Issue

Look inside for practical advice on separation science and thought–provoking commentary.

Teaching old drugs new tricks

James Frahill, who is a Research Analyst at the Pfizer Process Development Centre (Cork, Republic of Ireland), spoke to Bethany Degg of The Column about the role of the chromatographer in the pharmaceutical process development group at Pfizer.

The benefits and challenges of miniaturization

This article describes the advantages of miniaturizing laboratory instruments, as well as the challenges to adapt to and overcome.

UHPLC analysis of alkaloids and additives in dark chocolate

A simple, rapid, and robust UHPLC method for the simultaneous determination of polyphenols, methylxanthines, sweeteners, and flavouring substances, as well as some common preservatives, has been developed using an automated method scouting and method optimization workflow.

Incognito celebrates the power of the review article

Incognito presents his pick of the review articles that have helped him progress in his chromatography career.