| Everything about your chromatogram has changed and you just don't know why. The peaks have different retention times, peaks that are normally well resolved are now co-eluting, and the selectivity of all of the peaks has been altered. Taking one of these problems at a time is challenging, let alone all three! However, help is at hand... |
A GC-MS method which normally works well starts to exhibit broad peaks and there is a loss in sensitivity, what could possibly be causing the problem? Column contamination, an air leak, incorrect oven temperature,
the list could be lengthy... |
Problematic baselines. Pressure fluctuations. It's a nightmare that a lot of chromatographers have faced. Using the CHROMacademy HPLC troubleshooter we have solved this exact problem in the simple steps. Keep reading to find out how... |
