Subcritical water chromatography (SBWC) is seen as an increasingly enticing prospect to replace high performance liquid chromatography (HPLC) in industrial settings because of its low costs and environmental impact. Yu Yang of East Carolina University, in Greenville, North Carolina, USA, recently spoke to Lewis Botcherby of The Column about his work in this area, why companies should consider SBWC, and its role in pharmaceutical analysis.

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