calendar20 January 2016
Volume 12 Issue 1
The Column

20 January 2016 Issue

Look inside for practical advice on separation science and thought–provoking commentary.

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More from this issue...
The 2015 Instrumental Innovations

Incognito talks about reproducibility in research

Are your results reproducible?

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The benefits of TOF-HRMS in bioanalysis

Column overload in GC

Column overload is a very commonly encountered issue in gas chromatography (GC) for beginners. Changes in peak symmetry, generally observed as peak fronting, can be subtle in the sharp peaks generated by GC, but the result can be significant shifts in retention times, loss of resolution, and error in peak integration. LCGC Blogger Kevin Schug explains more.

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Finding the right calibration standards in GPC/SEC

Analyzing proteins using 2D LC

Gerd Vanhoenacker of the Research Institute for Chromatography (RIC) in Kortrijk, Belgium, has been conducting research into peptide mapping of therapeutic monoclonal antibodies (mAbs) using two-dimensional liquid chromatography (2D LC). He recently spoke to The Column about this work.

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The power of planar chromatography

Trace-level detection of organotins using GC–TOF-MS

This article presents a GC–TOF-MS method with soft ionization for trace-level detection and quantitation of organotins in complex matrices.

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Improving UHPLC method performance

Event review: 10th Balaton Symposium

A review of the 10th Balaton Symposium on High-Performance Separation Methods, which was held 2–4 September 2015 at the Hotel Azúr, Siófok, Hungary.

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Trends in bioanalysis using LC–MS–MS

News update: Detection method for early-stage ovarian cancer using UHPLC–HRMS

The benefits of pattern modulation in GC×GC, a detection method for early-stage ovarian cancer using UHPLC–HRMS, and the latest news in brief are featured in this issue.

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