Troubleshooting and practical help for chromatographers
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A recent chromacademy webcast looked at the critical evaluation of HPLC methods. Our viewers posed some interesting questions during the live Q&A so we wanted to share some of them here with you to hopefully encourage some critical evaluation of your own methods.
Sample preparation is required for a number of reasons, including, rendering the sample in the correct format for the analysis type, to reduce spurious peaks by removing interferences or matrix components...
Hydrophilic interaction chromatography (HILIC) is applicable to the separation of very polar, highly water soluble analytes which are often poorly retained (if at all) under reversed phase HPLC conditions...
Citrus, grapefruit, toffee, spice, apple, pear, biscuit, caramel… the list of flavors and aromas associated with beer is vast but how are they produced during the brewing process?
The issues related to column installation and how to properly prepare and install the column into the GC.