7 November 2017 Issue

Look inside for practical advice on separation science and thought–provoking commentary.

How much chemistry do you really know?

As an analytical chemist, how much do you know about the science?

Characterizing red chicory polyphenols using HPLC–MS/MS

Polyphenols are a well-known group of antioxidants widely diffused as secondary metabolites in plants, vegetables, and fruit. The Column spoke to Nicola Marchetti from the Department of Chemistry and Pharmaceutical Sciences at the University of Ferrara in Ferrara, Italy, about his research into the characterization of polyphenols in red chicory using high performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS).

Column selection for HPLC

This study demonstrates a new way to compare columns and select suitable replacement columns. The presented method will also allow the evaluation of different columns with the same method, as well as the evaluation of the robustness of the common method with different columns.

Advances in SFC and UHPLC conference review: Part 2

This review captures the highlights of the three-day Chromatographic Society meeting held in May 2017 and hosted by Pfizer in Sandwich, Kent, UK.

The benefits of UHP-SEC-MALS for polymer characterization

UHP-SEC offers multiple benefits for synthetic polymer characterization. However, its rapid, low-volume separation is more sensitive to column calibration errors and drift than traditional HP-SEC. Additionally, only a small selection of column chemistries are available. It is therefore essential to combine UHP-SEC with online, low-volume multi-angle light scattering instrumentation (UHP-SEC-MALS) to overcome these challenges.

News update: The latest news

The latest research news and news in brief are featured in this issue.