Reliably identify the presence of aggregates in characterization of mAbs
Monoclonal antibody (mAb) biotherapeutics have emerged as a critical class of drugs. The efficacy and safety of these biotherapeutics are highly dependent on maintaining a correct molecular structure. The presence of aggregates can lead to undesirable consequences, such as loss of therapeutic activity or even negative physiological effects. Identifying the presence of aggregate proteins in biotherapeutics is crucial.
Nobody understands better than Agilent
A unique non-destructive prescreening method using the Agilent Cary 60 UV-Vis spectrophotometer can quickly, easily, and reliably identify the presence of aggregate proteins.
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Featured Webinar:
How fab are your mAbs?
A complete aggregate analysis workflow for comprehensive, efficient, and reliable characterization of monoclonal antibodies
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New Application Note
Characterization of mAb Aggregation Using an
Agilent Cary 60 UV-Vis
and 1260 Infinity LC
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