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From Research to Routine - developing and delivering multiplexed protein mass spectrometry based tests of clinical utility
Despite a few decades of proteomics research and the apparent discovery of multiple protein biomarkers to support the diagnosis and treatment of patients, the number of biomarkers that have been developed to the stage of being used routinely in clinical practice is disappointingly low. In this presentation we will discuss key aspects of experimental design and implementation in order to maximize the chances of successful biomarker identification, characterization and quantitation.
For Research Use Only. Not for use in diagnostic procedures.
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This presentation will cover:
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Start at the end: identifying clinical need. |
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Protein biomarker discovery. |
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From candidate protein biomarkers to peptide MRM assays – advantages for biomarker evaluation. |
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Delivery of robust and routine peptide MRM assays – from sample preparation to test report. |
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Presenter
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Stephen Pennington, Ph.D.,
Professor of Proteomics, Founder, CEO and CSO Atturos Ltd. C/O
UCD Conway Institute University College Dublin |
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