LCGC North America Application Note Alert Having trouble viewing this email? Click here HPLC Rapid Separation of Basic Drug Compounds Under Alkaline pH Conditions on pH-Stable, Hamilton PRP™-C18 In this study a generic, 5-min linear gradient was used to separate six basic drug compounds on a short (50 mm) PRP-C18 column. Simultaneous Analysis of Monoclonal Antibodies The Thermo Scientific Vanquish Duo system for Dual LC can run two methods simultaneously on one instrument, regardless if identical chromatographic conditions are used.   Sample Preparation Automated SVOC Extraction Using Method 625.1 Learn how automated solid phase extraction (SPE) streamlines the analysis of semi-volatile organic compounds in wastewater, in compliance with U.S. EPA Method 625.1 Opioids in Urine, Fully Automated Analysis Automated hydrolysis, extraction, d-SPE clean-up, and introduction to LC–MS/MS of opioids in urine is shown using highly controlled conditions for an efficient workflow LipiFiltr® Cleanup for High-Lipid Food Samples The application shows the benefits of using the LipiFiltr® cartridge in multi-class, multi-residue analysis for a wide range of pesticides in complex, high fat samples. Rapid Phthalate Extraction from PVC This application note demonstrates a new technology for rapid extraction of phthalates from polyvinyl chloride.   GC VOCs from Water Headspace–trap with GC–MS for the identification and quantitation of a wide range of VOCs in water. The method meets all the requirements of US EPA Method 524.2 How Much Lightning in in Your Morning Jolt A study of the concentration of caffeine and other organic coffee marker molecules in fast food and home brewed coffee. Analyze More Semivolatile Samples per Shift Using Split Injection Using split injection can increase sample throughput for semivolatiles analysis because it provides faster oven cycle times due to the use of higher initial oven temperatures.   LC/MS Improving Results from Post-Column Flow Splitting Post-column flow splitting can cause excessive peak broadening and reproducibility issues for LC–MS scientists, but can be solved using modern splitting technology.