Fluorescein angiography of the left eye shows progression of retinal vasculature after intravitreal bevacizumab treatment. A. Before treatment, at 15 seconds, minimal vascularization and a neovascular proliferation near the optic disk are seen at 6 weeks of age (38 weeks postmenstrual age); this eye was treated the same day. B. Six weeks after treatment, during the first minute, growth of the retinal vasculature, hyperfluorescence due to vascular incompetence, formation of vascular loops, and absence of the foveal avascular zone (FAZ) are seen. C. Thirteen weeks after treatment, there is further growth of the retinal vasculature and formation of the FAZ.

Fluorescein angiography of the left eye shows progression of retinal vasculature after intravitreal bevacizumab treatment. A. Before treatment, at 15 seconds, minimal vascularization and a neovascular proliferation near the optic disk are seen at 6 weeks of age (38 weeks postmenstrual age); this eye was treated the same day. B. Six weeks after treatment, during the first minute, growth of the retinal vasculature, hyperfluorescence due to vascular incompetence, formation of vascular loops, and absence of the foveal avascular zone (FAZ) are seen. C. Thirteen weeks after treatment, there is further growth of the retinal vasculature and formation of the FAZ.

Fluorescein angiography of the left eye shows progression of retinal vasculature after intravitreal bevacizumab treatment. A. Before treatment, at 15 seconds, minimal vascularization and a neovascular proliferation near the optic disk are seen at 6 weeks of age (38 weeks postmenstrual age); this eye was treated the same day. B. Six weeks after treatment, during the first minute, growth of the retinal vasculature, hyperfluorescence due to vascular incompetence, formation of vascular loops, and absence of the foveal avascular zone (FAZ) are seen. C. Thirteen weeks after treatment, there is further growth of the retinal vasculature and formation of the FAZ.