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CASE STUDY: In-house Mass Spectrometry Becomes Essential in Supporting Research and Process Development
| The Company |
Macrogenics, Inc., a clinical-stage biopharmaceutical company |
| The Challenge |
Macrogenics had numerous programs that were rapidly moving towards the clinic and wanted to routinely review mass spectrometry data. However, full MS analysis outsourced to its CRO was taking too long and costing too much. |
| The Solution |
Macrogenics brought MS capabilities in-house for confirmation and characterization of its biotherapeutic candidates. |
| The Results |
Accelerated analytical turnaround times
- Top-down intact mass analysis from
1-3 weeks to 2-3 days
- Bottom-up peptide mapping studies from 3-6 weeks to about 1 week
Eliminated high-cost outsourcing of mass spectrometry analyses
- $400 per sample for outsourced top-down MS analysis
- $3,000 per sample for outsourced
LC-MS peptide mapping studies |
We hope you find this information valuable.
Waters Biopharmaceutical Team
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