Hear from leading experts in the field of hydrogen deuterium exchange mass spectrometry (HDX-MS) as they discuss their experience utilizing this tool—both to simplify the process of selecting the most promising new biopharmaceutical entities for therapeutic intervention, and to understand the interactions between a therapeutic and its biological target.

Dr. Anand, the foremost expert on HDX-MS at the National University of Singapore, presents his recent work using HDX-MS to identify lead fragment compounds through protein-ligand binding studies. In addition, he details exciting new research to uncover novel sites within macromolecular assemblies, including viruses with high potential to serve as targets for new interventional therapies.

Ms. Zhang of the Lilly Biotechnology Center discusses her work on on epitope and paratope mapping studies of monoclonal antibodies using HDX-MS, and its ability to advance proteins through biopharmaceutical drug discovery.

Watch the on-demand video now to learn more about HDX-MS and how you can leverage it to understand the dynamics of higher order structure (HOS) of biotherapeutics.

Sincerely,

Waters Biopharmaceutical Team