A Unique Workfl ow for Linearity Testing using Automated Sample Preparation and UHPLC | January 20, 2011 at 11:00 EST; 8:00 PST; 4:00 PM GMT

Register Free at
http://www.pharmtech.com/osmoticcontrolled


Event Overview:
Several formulation design options are available to control or modulate the drug release from a dosage form. The majority of oral dosage forms fall in the category of matrix, reservoir, or osmotic systems. In a hydrophilic matrix system, the drug is embedded in a polymer matrix and the release takes place by diffusion of the drug into the hydrated polymer gel layer and erosion of the gel layer into the release medium. In contrast, reservoir systems have a drug core surrounded or coated by a water-insoluble, but permeable rate-controlling membrane. However, factors such as pH, the presence of food, and other physiological factors may affect drug release from conventional, matrix and reservoir controlled-release systems. Osmotic systems utilize the principle of osmotic pressure for the delivery of drugs. Drug release from these systems is independent of pH and other physiological parameters to a large extent, making it possible to modulate the release characteristic by optimizing the properties of drug and the coating system.

In this 60-minute educational webcast, formulation development experts will address the theories and basic formulation principles behind these various drug release systems including advantages and disadvantages of each.  Recent advances in osmotic delivery, including case study examples, will also be addressed.

Key Learning Objectives:
  • Learn about recent advances in the osmotic controlled release of oral drug delivery systems
  • Gain an understanding of the theories and basic formulation principles behind drug release systems
  • Hear from industry peers about case studies that illustrate successful projects using some of these drug delivery systems
For questions, contact Kristen Farrell at kfarrell@advanstar.com

Who Should Attend:
  • Formulation scientists
  • R&D managers, directors, technical personnel, and group leaders engaged in formulation and formulation development
  • Process development scientists, managers, directors, and group leaders
  • Section heads and project managers
  • Technical personnel involved in process optimization

Speakers:

Don Barbieri,
Associate Director of Formulation and Process Development,
Patheon Inc.

Elizabeth Tocce,
Senior Engineer,
Dow Chemical Co.

Moderator:
Angie Drakulich
Editorial Director
Pharmaceutical Technology