The bioproduction industry is evolving from targeting highest titers to achieving more control over protein quality and process consistency. Both chemically defined media and biologically derived peptones can contribute to variability in cell culture process due to impurities and inherent lot-to-lot variability. This podcast will discuss the approaches BD has taken to identify key performance drivers in an effort to stabilize performance across production batches in chemically defined media and feeds as well as peptone supplements.