Determination of Pesticide and Mycotoxin Residues in Dried Cannabis Flower: LC-MS/MS and GC-MS/MS Methodology to Meet the Recommended AOAC Regulatory Requirements for US States and Canada

The methodology presented in this application note is suitable, with a few exceptions, to determine pesticides and mycotoxins currently regulated by any of the US states or Canada at the AOAC-recommended LOQ.

UPLC Separation for the Analysis of Cannabinoid Content in Cannabis Flower and Extracts

This application note presents the modification of a simple isocratic HPLC separation of 16 cannabinoids to a separation under UPLC conditions. Conversion of the method to UPLC operation provides a greater than 2-fold increase in testing productivity while maintaining the linearity, selectivity, and suitability observed in the HPLC separation.

Terpenes in Hemp and Cannabis Determined Using EI GC-MS/MS

The Xevo TQ-GC for the analysis of terpenes using EI GC-MS/MS was demonstrated using a simple microextraction of hemp and cannabis plant material. The benefits of MS and MS/MS acquisition modes for both method development and routine quantitation were shown to be applicable to multiple elements of terpenes analysis.