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Rates of testing and diagnosis are declining* and may be increasing your plan’s exposure to the high cost of osteoporosis-related fractures1,2
*Among women age 65 and over from 2009 to 2014.
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Dear [Insert Customer Name],
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Postmenopausal osteoporosis diagnosis rates declined from 2009-2014.2 Yet, osteoporosis-related fracture rates are on the rise.3 Recent data show that total fracture rates increased beginning in 2016.3
†Data from female Medicare beneficiaries with evidence of fracture: 100% sample for 2010-2012, 5% sample for 2006-2009.
‡Study results from 4140 postmenopausal women, in the Netherlands, with a known fracture history.
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Patients who were persistent on medication had an ~41% greater decline in hip fracture rates compared with patients who were nonpersistent.1,§
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Reduction of Fracture Rate Ratio (FRR) Between Persistent and Nonpersistent Patients1,§
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§The study examined the relationship between persistent osteoporosis medication use and fracture risk among elderly female Medicare beneficiaries aged ≥ 66 years (n = 294,369) diagnosed with osteoporosis using Medicare claims January 1, 2009, to June 30, 2011. Persistent medication use was defined as continuous use (no gap ≥ 60 days) for 1 year or longer. (Includes any prescription osteoporosis medication FDA approved through December 2011.)
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Persistent use of osteoporosis medication was associated with reduced risk of fracture and significantly lower total healthcare costs.1
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Aim to improve persistence to osteoporosis medications to help your members reduce their risk of fracture and associated healthcare costs.1
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References: 1. Liu J, Guo H, Rai P, Pinto L, Barron R. Medication persistence and risk of fracture among female Medicare beneficiaries diagnosed with osteoporosis. Osteoporos Int. 2018;29:2409-2417. 2. U.S. Department of Health and Human Services. Bone Health and Osteoporosis: A Report of the Surgeon General. Rockville, MD: U.S. Department of Health and Human Services, Office of the Surgeon General, 2004. 3. Balasubramanian A, Zhang J, Chen L, et al. Risk of subsequent fracture after prior fracture among older women. Osteoporos Int. 2019;30:79-92. 4. Van Geel TACM, Van Helden S, Geusens PP, Winkens B, Dinant G-J. Clinical subsequent fractures cluster in time after first fracture. Ann Rheum Dis. 2009;68:99-102.
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Amgen Inc.
One Amgen Center Drive
Thousand Oaks, CA 91320-1799
www.amgen.com
© 2020 Amgen Inc. All rights reserved.
USA-785-81449 11/20
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