Spironolactone efficacy may be similar to oral antibiotic Tx
Several retrospective analyses indicate spironolactone may have similar efficacy to oral antibiotics in the treatment of acne in women, but underuse of this off-label treatment option may be due to lack of efficacy evidence. The two options should be directly evaluated in future studies to guide practice.
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Topical probiotics may restore skin microflora, decrease acne lesions
Topical probiotics could promote a positive bacterial balance in the skin – similar to how oral probiotics increase diversity of flora in the gut – and may improve skin conditions, such as acne, says in a recent review.