In this Q&A, Dr. Roy Fleischmann, the primary investigator for the phase three clinical trial of upadacitinib (Rinvoq, AbbVie), compares the new rheumatoid arthritis treatment to other treatments.
Triple therapy and methotrexatebased biologic diseasemodifying antirheumatic drug (DMARD) combinations were superior to methotrexate alone for both American College of Rheumatology (ACR50) response and remission in patients with rheumatoid arthritis, say researchers writing in Arthritis Research & Therapy last month.
AbbVie announced on Friday that the Food and Drug Administration approved the oral once-daily JAK inhibitor Rinvoq (upadacitinib) for adults with moderate to severe active rheumatoid arthritis who have had an inadequate response or intolerance to methotrexate.
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