BioPharm International’s Biopharma Knowledge Resources Newsletter:
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BioPharm
August 28, 2018
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In This Issue

Build your biopharma development and manufacturing knowledge base with the latest whitepapers, application notes, posters, and other educational resources from biopharma industry suppliers.

 Featured App Note

Antibody Affinity Extraction for HCP Analysis

Ken Hoffman and Eric Bishop, Cygnus Technologies, LLC

Antibody Affinity Extraction (AAE) is a superior alternative to 2D Western blot for demonstrating host cell protein (HCP) antibody coverage and reactivity to those HCPs that persist through the downstream purification process.

Downstream Processing

Removal of mAb Aggregates with TOYOPEARL® Sulfate-650F Resin

Tosoh Bioscience LLC

In this study, TOYOPEARL® Sulfate-650F, a strong cation exchange chromatography resin, was used to capture and remove monoclonal antibody (mAb) aggregates and host cell proteins to improve the purity of the mAb eluate post-protein A in a single polishing step.

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