Build your biopharma development and manufacturing knowledge base with the latest whitepapers, application notes, posters, and other educational resources from biopharma industry suppliers.

Meet Stunner: The One-Shot Protein Concentration and Sizing Combo

Unchained Labs

Stunner is the one and only instrument that gives you ultraviolet–visible spectroscopy (UV/Vis) concentration and dynamic light scattering (DLS) sizing at the same time. Know in minutes if your protein sample is good to go.

Optimal Protein Purification Using Multivariate Scouting

Kevin Thornton, Bio-Rad

Learn how the NGC Chromatography System with new multivariable scouting features in ChromLab Software v6.0 was used to rapidly develop optimal experimental conditions for an automated antibody purification workflow.

Antibody Drug Conjugate Purification Using TOYOPEARL^® PPG-600M Resin

Tosoh Bioscience LLC

In this application note, antibody drug conjugates (ADCs) were separated into groups with low, medium, and high drug-to-antibody ratios (DARs) using TOYOPEARL PPG-600M resin with a three-step gradient.

Fully Automated Digestion, Separation, and Analysis of the Human Prolactin Receptor Transmembrane Protein by LC-MS/MS

Shimadzu

Detection and quantification of peptides from transmembrane proteins is important for detection of biomarkers and new protein-based drugs. This paper presents a fully automated online digestion and liquid chromatography-mass spectrometry-multiple reaction monitoring (LC-MS/MRM) analysis of two model transmembrane proteins, a method that improves reproducibility and decreases chances of contamination.

Characterization of AAV Gene Therapy Vectors Using TEM

Vironova

Automated transmission electron microscopy (TEM)-based image analysis can quickly provide accurate data to facilitate process development decisions for removal of typical contaminants in adeno-associated virus (AAV)-based gene therapy.

• Broken particles
• Debris
• Residual DNA
• Capsid content (full/empty)
• Aggregates