BioPharm International’s Biopharma Knowledge Resources Newsletter:
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BioPharm
March 26, 2020
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In This Issue

Build your biopharma development and manufacturing knowledge base with the latest whitepapers, application notes, posters, and other educational resources from biopharma industry suppliers.

 Featured App Note

Analysis of Glycopeptides Using a Compact MALDI-DIT Mass Spectrometer

This application shows the ability of an ultra-compact MALDI-DIT MS to obtain full information for components like glycopeptides, which have large molecular sizes and complex structures.


Analytics

Using Digital MFC Capabilities to Improve Bioprocessing Results

This new whitepaper from Brooks Instrument describes the inner workings of digital MFCs and their ability to gather, generate, and communicate a range of process data. The content reviews ways to utilize MFC device data to improve process control, system uptime, diagnostics, preventive maintenance, and bioprocessing yields.

 

Effects of Buffer Composition When Using Mixed-Mode Chromatography

Multiple separation steps are often required to eliminate product- and process-related impurities impacting biopharmaceuticals. This study shows that buffer composition has an effect on target purity and recovery when using Nuvia aPrime 4A, a mixed-mode resin. A broad range of impurities can be removed in a single chromatography step when using this resin.


Quality

How to Avoid Contamination in Pipetting

Preventing contamination in pipetting is paramount to achieving reliable results. It requires identification of the potential contamination mechanisms in order that they can all be addressed.


Manufacturing

Successful Wetting for Filter Integrity Testing in Volume-Restricted Systems

Pall’s application note offers clear guidance for the successful wetting of filters in challenging situations where low volumes of wetting fluid must be used, such as filters on single-use systems.

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