LCGC Europe Weekly Update
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5 December, 2019
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LCGC Blog

The Exposome: Is It Too Vast to Tackle?

I run into scientists all the time who have never heard the term exposome. Most are not intimately connected in the analytical world; these days, analytical scientists seemingly expect “ome” and “omics” to be tacked onto pretty much anything. But “omics” is certainly more than a fad, and most in the business can connect with common concepts like proteomics, metabolomics, lipidomics, and genomics.
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Reliable GC Analysis of Triglycerides in Edible Oils
With best-in-class thermal stability, new Rxi-65TG columns are the top choice for accurate analysis of triglycerides (acylglycerols) in edible oils. Novel chemistry and cutting-edge manufacturing allow Rxi-65TG columns to produce less bleed at a higher maximum temperature (370 °C) than competitor columns produce at their lower maximum temperature (360 °C). Less interference from column bleed means more accurate and sensitive detection of edible oil triglycerides.
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Features

Minimizing Fluctuating Peptide Retention in 2D-LC: How to Address a Moving Target

Retention of peptides is strongly dependent on solvent composition in reversed-phase separations with gradient elution. In this instalment we provide tips, tricks, and suggestions for best practices to help minimize retention time variations over time. Read more


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Micro Pillar Array Column Technology Resource Center
An online resource with useful tools and practical information for separation scientists who want to find out more about how micro-pillar array columns can benefit the laboratory scientist in practice. The site provides useful technical notes, video interviews, and executive summaries of cutting-edge applications from leading practitioners in the field of proteomics and biopharmaceutical applications.
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mORE Features

Online LC–GC: The Ultimate "GC Connection"

In this instalment of “GC Connections”, the ultimate connection, multidimensional chromatography with HPLC as the first dimension and GC as the second, is discussed. Read more

News

Analysis of White Oils Using AgLC×GC

Researchers have developed two new methods for the analysis of MOAHs in highly purified mineral oil fractions (white oils) using comprehensive AgLC×GC, one method uses FID, while the other uses VUV. Read more


FEATURED PRODUCT

NEW Sample automation & concentration platform

Centri® – a multi-technique sample automation, pre-concentration and injection platform for GC that delivers enhanced analytical sensitivity and higher throughput for VOC and SVOC analysis in liquid, solid and gas samples. / Learn more /


APPLICATION NOTE

Multi-Attribute Analysis of Monoclonal Antibodies

Multi-attribute analysis combines protein A affinity chromatography, SEC, and LC/MS in a 3D setup for assessment of features including mAb titer and size variants. / Read more /

UPCOMING WEBCASTS

Data Management and Integrity Expectations from the World Health Organization and PIC/S

Tuesday, Dec. 10, 2019 at 10am EST | 9am CST | 3pm GMT | 4pm CET
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Thorough and Reproducible Analytical Characterization of Innovator and Biosimilar Pair

European and North American Broadcast: Wednesday, Dec. 11, 2019 at 2pm GMT | 3pm CET | 2pm EST| 1pm CST | 11am PST
Asia Pacific: Available On-Demand on Dec. 12, 2020
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The CHROMacademy Essential Guide Webcast: Understanding GC Sample Introduction

Thursday 12th Dec. 2019, 11:00am EST | 8:00am PST | 4:00pm GMT | 5:00pm CET
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Editors’ Series: Streamlined Characterization of Antibody–Drug Conjugates by Two-Dimensional (2D) and Four Dimensional (4D) LC–MS

Thursday, December 12, 2019 at 11am EST | 8am PST | 4pm GMT | 5pm CET
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Capillary Flow LC–MS Using Micro Pillar Array Columns: Combining Nano Flow Sensitivity with Analytical Flow Robustness and Throughput

Friday, Dec. 13, 2019 at 10am EST | 9am CST | 3pm GMT | 4pm CET
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ON DEMAND WEBCASTS

Good Water Practices for Reliable LC–MS and ICP-MS Analyses


Platform Purification Approaches for the Production of Complex Biologics


Access Monoclonal Antibody Quality Attributes with HRMS Analytical Power


In a Pickle with Pesticides Sample Prep? Achieve Higher Recoveries with Rapid, Automated Extraction of Any Food Matrix


Non-targeted Screening for Environmental Water Quality Monitoring


Workflows for Released N-Glycan Analysis and Sialic Acid Quantitation of Biotherapeutics

 

Thermal Desorption-Direct MS: A Breakthrough in Analysis Speed and Throughput


Editors’ Series: Strategies for Improved Pharmaceutical Sample Preparation


In a Pickle with Pesticides Sample Prep? Achieve Higher Recoveries with Rapid, Automated Extraction of Any Food Matrix


How to Approach Preparative LC for Compound Purification in the Research and Development Laboratory


Identifying and Quantifying Aspartate and Iso-Aspartate Isomers and Other Difficult PTMs in Proteins


RPLC Method Development Strategies Using Stationary Phase and Mobile Phase Screening, and Some Helpful Tools and Tips


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