LCGC Application Note Alert
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LCGC Global
Optimized methods for µPAC™ capLC columns
PharmaFluidics’ µPAC™ capLC is evaluated for different user needs ranging from 12 samples per day in comprehensive mode to 65 samples per day in throughput mode.
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Assessment of µPAC™ capLC column performance
PharmaFluidics introduces a new µPAC™ capLC column that offers unprecedented performance and that given its low backpressure can be used with flow rates of up to 15μL/min.
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HCP monitoring in downstream process samples
µPAC™ technology has been used for analysing HCP impurities originating from recombinant expression systems used in the production of mAb based biotherapeutics.
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Routine proteome analysis using μPAC™ columns
PharmaFluidics also offers a 50 cm long µPAC™ column which is perfectly suited to perform more throughput analyses with shorter gradient solvent times.
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Metabolomic profiling using µPAC™ columns
Overall gain in performance and increase in detection sensitivity that can be achieved for the separation of plant metabolite extracts by using µPAC™ columns.
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Skin ceramide profiling using μPAC™ columns
Analyzing skin ceramides using PharmaFluidics’ µPAC™ column technology reveals a substantial structural diversity and isomeric resolved sphingolipids.
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μPAC™ column robustness in bottom-up proteomics
PharmaFluidics’ µPAC™ columns have the potential to be less prone to sample related column failure and to withstand more sample injections without losing performance.
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Separation performance of µPAC™ columns
Monitoring the excellent separation performance of PharmaFluidics’ µPAC™ columns by using peptide retention time calibration mixtures for bottom-up proteomics.
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