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LCGC North America | e-Separation Solutions
December 10, 2015
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The LCGC Blog

The LCGC Blog: Why Column Screening is Better than Mobile-Phase Screening for LC–MS Method Development
I now hold to be true: It is much more efficient to screen column chemistries to achieve optimum separations for a set of target analytes, than it is to play with different mobile-phase conditions on a single column.
LCGC TV
LCGC TV: Robert T. Kennedy, Part 4: Analytical Chemists in the Field of Metabolomics
In this video, Robert T. Kennedy of the University of Michigan discusses the challenges of metabolomics – coping with data overload, dealing with small amounts of sample, and improving analysis through derivatization. He also talks about what it's like to be an analytical chemist in a biologist's world, and convincing the “omics” community of the importance of chromatography.
University students and staff get 5 Years of Free Access to CHROMacademy made possible by Agilent Technologies – the world's premiere measurement company.
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Featured Articles

Split-Vent Traps: GC's Dirty Secret
In gas chromatography split injection systems, as much as 99% or more of the injected sample never enters the column: It is released downstream of the inlet where it can encounter and possibly perturb precision gas control devices. The split-vent trap acts to prevent or at least moderate such effects. This article addresses the operation and maintenance of split-vent traps.

Separation Science in Drug Development, Part III: Analytical Development
An overview of modern practices of separation science in small-molecule drug development, focusing on HPLC method development.
Neonicitinoids from Chem Service
Neonicotinoids are a group of systemic agricultural insecticides resembling nicotine in structure. The most widely used is imidacloprid. Recently, use of neonicotinoids has been associated with the decline in the bee population.
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Featured Products
New OMNISEC GPC/SEC System LECO's Pegasus® GC-HRT 4D
For absolute molecular weight characterization of synthetic and natural polymers, as well as determination of aggregation and oligomeric state of proteins with the lowest of sample concentration requirements. Learn more The Pegasus® GC-HRT 4D combines the highest performance GCxGC and the most accurate TOFMS on the market with High Resolution Deconvolution® (HRD®). Users are able to find more analytes than ever before and identify components with ultimate confidence. Learn more
 
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