The LCGC Blog
The improved performance of chromatographic detectors, most notably mass spectrometers, has enabled many advances in analytical science, however, one such advance may be given less prominence than perhaps it should. Learn more
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Revolutionary Light Scattering Detector from Tosoh Bioscience
The LenS3 MALS detector offers the highest sensitivity (2 ng of sample loading for mAbs) and Rg values below 10 nm!
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Featured Articles
The high levels of non-volatile salts typically used in ion-exchange separations are incompatible with mass spectrometry. But the desire to directly couple these two powerful techniques has prompted researchers find solutions to this problem. Here are three approaches.
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Flexibility and Durability in a Column
FlexFire is designed to deliver supreme durability and maximum flexibility with porous 1.6, 2.6 and 5 µm particles for UHPLC and HPLC. With improved endcapping technology and new design of porous silica, FlexFire withstands the harshest conditions and delivers use after use. With a variety of functional groups and particle sizes, FlexFire is designed for scalability and transferability. Demo columns are available.
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This integrated analytical approach combines HPLC–MS/MS and GC–MS/MS to detect 36 PFAS migrating into food simulants from packaging.
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Become the lab expert with our FREE interactive GC Troubleshooter
Get answers fast, reduce downtime and improve efficiency with a little help from our practical GC troubleshooting videos.  . Start GC Troubleshooting
HILIC has rapidly evolved into a practical technique. For analyzing highly polar compounds, HILIC can be far more straightforward than GC or reversed-phase LC with derivatization, and can lead to a simpler final method with robustness comparable to that of reversed-phase LC.
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More Featured Articles
The field of sample preparation is undergoing revolutionary change, largely governed by the need for miniaturization while maintaining high selectivity and high analyte enrichment. How up-to-date are you in the advances of sample preparation for chromatographic analysis?
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Exclusive Interview from HPLC:
Latest Advancements and Benefits of micro Pillar Array Columns.
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The impact of ionic strength, buffer capacity, and pH-response on the retention behavior and peak shape of mAb species characterization is evaluated for IEX-MS. The aim of the present study was to understand the impact of ionic strength, buffer capacity, and pH-response on the retention behavior and peak shape of mAb species.
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Advances in Chromatography for Macromolecule Analysis
An online resource with useful tools and practical information for separation scientists who want to find out more about Macromolecule Analysis. The site provides useful webcasts, videos, application notes, ebooks, and more from leading practitioners in the field of chromatography.
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FEATURED PRODUCTS
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The highest performance LC/TQ available with Agilent's third generation iFunnel design, ideally suited for peptide quant as well as multiresidue applications that require ppt sensitivity. The combination of utmost sensitivity, extended mass range, ease of maintenance with VacShield technology, and the power and flexibility of MassHunter makes this the system of choice for demanding applications.  / Click here for further information / |
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Daicel introduces three new polymeric phases for use in achiral separations. These phases combine polymeric robustness with unique chemical composition to ensure new and reliable separations. DCpak P4VP, PBT, and PTZ  / Learn more / |
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FRITSCH PULVERISETTE 11 For homogenization or cryogenic grinding of moist, oily, fatty materials, dry, soft, medium-hard & fibrous samples, including: Food, feed, pharmaceuticals, & more. The grinding vessel, lid, & knife are dishwasher safe & autoclavable.  / Learn more / |
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Thermal desorption tubes from Markes are manufactured to the highest quality, delivering optimum results time after time. Suitable for all TD applications, including environmental air monitoring, fragrance analysis, and breath monitoring.  / Learn more / |
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Thermo Fisher Scientific and PSS have developed a native WinGPC-Chromeleon™ CDS data connector to enable Chromeleon 7.2 CDS users to process GPC/SEC data in WinGPC Data Evaluation.
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/ Download application note /
/ Download application note /