Pharmaceutical Technology ePT Weekly
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PharmTech
November 07, 2019
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In this issue:

Considering Protein and Peptide Delivery

Biopharma Dominates ISPE’s 2019 Facility of the Year Awards

HTL to Invest in Production Facility for Injectable Grade Sodium Hyaluronate


Top Stories

Roche and Dicerna Enter Collaboration Worth up to $1.67 Billion

The partnership will center on the development and commercialization of DCR-HBVS, Dicerna’s investigational therapy in Phase I clinical development, using its proprietary RNAi platform technology.
/ read more /


Cystic Fibrosis Foundation Announces $500
Million Path to a Cure Research Project

The project will seek to deliver treatments for the underlying cause of cystic fibrosis through submitted proposals from potential collaborators..
/ read more /

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Industry News

New Study Reveals How Drug Resistance Could Advance Antibiotic Therapies

Published on Oct. 29, 2019, the study focuses on the multidrug-resistant bacterium Pseudomonas aeruginosa (P. aeruginosa) and how it can be used to develop new and sustainable antibiotic treatments.
/ read more /


SeraNovo Signs License Agreement with Carna Biosciences

Start-up company, SeraNovo, has revealed that it has signed a license agreement with Carna Biosciences to expand the existing collaboration and jointly develop an oral formulation of Carna’s kinase inhibitor with increase bioavailability.
/ read more /


More Industry News

Supplier News

HTL to Invest in Production Facility for Injectable Grade Sodium Hyaluronate

The new Javené, France-based facility is expected to increase the company’s production capacity of injectable grade sodium hyaluronate obtained by fermentation by 2.5 times.
/ read more /


Cycle Pharmaceuticals, Catalent Partner on Rare Disease Treatment

The companies will develop innovative formulations for drugs to treat rare diseases using Catalent’s oral disintegrating tablet technologies.
/ read more /


More Supplier News
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Bio/Pharma News

Biopharma Dominates ISPE’s 2019 Facility of the Year Awards

Breaking with tradition, a compounding facility won for overall operational excellence, while biopharma facilities took home awards in various categories.
/ read more /


Biogen, Alkermes Get FDA Approval for MS Drug

FDA has approved Vumerity (diroximel fumarate), a new oral drug for relapsing forms of multiple sclerosis.
/ read more /

More Bio/Pharma News

Regulatory News

Study Suggests that More Pharma Companies are Ready for DSCSA

Showing gains of 54% compared with 2018, results from a 2019 study showed that nearly three-quarters of pharma barcodes meet Drug Supply Chain Security Act requirements.
/ read more /


FDA Releases Report on Underlying Causes of Drug Shortages

The report focuses on information from stakeholders, published research, and economic analysis of market conditions from an analysis of drug shortage data and development of recommendations by the inter-agency Drug Shortage Task Force led by FDA.
/ read more /


More Regulatory News

FEATURED TOPICS

FORMULATION

Considering Protein and Peptide Delivery

New approaches seek to address formulation and delivery challenges for these complex molecules.
/ read more /

MANUFACTURING

Continuous Manufacturing: Addressing the Tough Questions

Although continuous approaches offer significant benefits for some products and processes, batch manufacturing is not going away any time soon.
/ read more /



PEER-REVIEWED RESEARCH

Degradation Pathways: A Case Study with Pegylated L-Asparaginase

It is important to address manufacturing problems associated with the shorter shelf-life of pegylated L-asparaginase (pegaspargase) upon long-term storage in the form of a solution.
/ read more /

DRUG DELIVERY

Advanced Cell Penetrating Peptide Systems for Gene Therapy

Intracellular strategies offer an effective alternative approach to deliver a range of therapeutic proteins.
/ read more /


UPCOMING WEBCASTS


An Integrated Approach to Spray Drying: From Scale-Up to Manufacturing
November 19, 2019 at 11am EST | 8am PST | 4pm GMT | 5pm CET
Register Now


Replacing Settle Plates with Active Air Sampling
Wednesday, November 13, 2019 at 10am EST | 9am CST | 3pm GMT | 4pm CET
Register Now


ON DEMAND WEBCASTS

How to Approach Preparative LC for Compound Purification in the Research and Development Laboratory
On Demand
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Choosing The Right CDMO For Late-Phase Clinical Trials
On Demand
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New Research Revealed on a Promising Functional Alternative to Surfactants within Biologic Formulations
On Demand
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Data Integrity and the Next Level of Connectivity in a Modern Lab
On Demand
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A Roadmap for Early Development to Commercial Manufacturing
On Demand
Learn More


An Integrated Approach to Rapidly Delivering Bioavailability-Challenged Small Molecules to the Clinic
On Demand
Learn More


New Draft USP <922> Chapter for Water Activity Measurement
On Demand
Learn More


Workflow Breakthroughs that Are Improving Data Quality and Efficiency and Changing Pharmaceutical Analysis
On Demand
Learn More



Events

Outsourcing & Supply Chain–A 360° View

November 12–13, 2019

Validation University

November 25–26, 2019

Twin Screw Workshop

December 4–5, 2019


more events

eBOOKS

Biologics and Sterile Drug Manufacturing 2019

The editors explore novel technologies for the formulation, manufacture, purification, and delivery of sterile small- and large-molecule drugs including single-use systems, facilities and equipment, contamination issues, and process analytics.


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