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PRODUCTION TRENDS
Closed systems for aseptic fill and finish were featured at INTERPHEX 2019.
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BEST PRACTICES IN ASEPTIC PROCESSING
Microbial identity data can be critical for determining contamination sources.
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The author reviews current approaches to sterile containment and compares several sealed transfer and barrier techniques, including isolators, restricted access barrier systems, and split butterfly valve technology.
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Alternatives to time-consuming, error-prone operations promise to reduce vaccine manufacturing costs and improve facility flexibility.
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PACKAGING
Contract packagers expand operations and services to accommodate growing need.
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More Packaging
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IN THE NEWS
The UK's Centre for Process Innovation (CPI) is collaborating with partners GSK and AstraZeneca to establish a continuous wet granulation manufacturing facility for small-scale development of oral solid-dosage pharmaceuticals.
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The European Commission has published a strategy that will form the basis for the European Union's policy on pharmaceuticals in the environment.
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EDITOR'S PICKS
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The ChargePoint Single Use Passive and ChargeBag create a single-use system for contained and sterile transfer of pharmaceutical powders between process steps or facilities.
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The Quartic Platform is a new, AI-powered smart manufacturing platform that can be integrated into legacy facilities and manufacturing processes.
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Equipment Showcase
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Leistritz manufactures twin screw extruders and systems for continuous mixing/devolatilization of API's with excipients. Lab scale and production scale equipment is available, and applications include melt extrusion and granulation. A variety of upstream and downstream equipment is available. Services include a process NJ development laboratory and ongoing training/workshops.
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UPCOMING WEBCASTS
Requirements for Fully-Integrated Service Offerings in a HPAPI and Cytotoxic Environment
Two Live Events: Tuesday, May 28, 2019, at 10am JST | 9pm EDT | 6pm PDT
Tuesday, May 28, 2019, at 5pm JST | 10am CEST
 Register now
Geographic Advantage: Accelerating Clinical Supply in China and Global Trials
Thursday, May 9 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST
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Beating the Clock: Case Studies in Expediting Biologic Development
Tuesday, May 7, 2019 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST
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Sustainable Sourcing & Supply Chain Engagement in Pharma
Tuesday, May 7, 2019 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST
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Approaches to Analyze and Understand 1–100 μm Particles/Aggregates in Biotherapeutics
Tuesday, April 23, 2019 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST
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EVENTS
April 23–24, 2019 | Washington, DC
April 30–May 2, 2019 | Chicago, IL
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eBOOK
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The editors explore new tools for bio/pharma lab studies—such as robotics, augmented reality, and advanced instrumentation—as well as best practices for method development, multiple attribute monitoring, lab mixers, and raw material testing.
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