Pharmaceutical Technology EPR Monthly Issue:
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Pharm Tech
October 16, 2019
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PRODUCTION TRENDS

Process Modeling Tools Find Use in Bio/Pharma R&D and Manufacturing

Systems-based pharmaceutics case studies, challenges, and new uses were discussed at PSE’s Advanced Process Modeling Forum.
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Using Simulation to Optimize Fill/Finish Equipment

Optima Packaging explains its Industry 4.0 approach to process design.
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FROM THE ARCHIVE: PROCESS MODELING

Flowsheet Models Modernize Pharmaceutical Manufacturing Design and Risk Assessment

In-silico design facilitates process optimization and evaluation of process control strategies.
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Using Model-Predictive Design in Solid-Dosage Manufacturing Processes

Models and modeling software gain a foothold in solid-dosage manufacturing process design.
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Design Space Characterization and Risk Assessment Through Mechanistic Modeling

Mechanistic process and product modeling turns data into knowledge that can be extrapolated with known confidence.
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IN THE NEWS

Siemens Plans to Acquire PSE

PSE, a supplier of advanced process modeling software and services, plans to become part of Siemens Digital Industries.
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Janssen Uses Insilico’s Digital Twins for Cell Culture

Janssen will use Insilico’s digital models of cells to accelerate cell-line development for biologics manufacturing.
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UK Collaboration Uses a Direct Compression Digital Twin to Speed OSD Formulation

CPI, the University of Strathclyde, GSK, and AstraZeneca Collaborate on a CDC digital twin for formulation optimization.
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PACKAGING

Automation on Display at Healthcare Packaging Expo

Automated fill/finish and inspection equipment displayed at PMMI’s Healthcare Packaging Expo improves quality and efficiency.
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More Packaging


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We’re Exhibiting – 2019 SupplySide West
Federal Equipment Company will be exhibiting at SupplySide West, booth #5736, October 17-18, 2019, at Mandalay Bay in Las Vegas, NV. Stop by our booth to discuss your equipment needs. You can save on show registration with the code: EX10SSW.
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EDITOR'S PICKS

Process Analytics Software Displays Live Production Views and Historical Analysis Remotely

TrendMiner 2019.R3 displays a customized, actionable dashboard with a real-time view of the production process.
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Powder Dosing Unit Reduces Waste

MG America’s Extrudor system for its capsule filling equipment uses only one dosing disk per capsule size for all dosages.
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Sponsor Showcase

Leistritz manufactures twin screw extruders and systems for continuous mixing/devolatilization of API's with excipients. Lab scale and production scale equipment is available, and applications include melt extrusion and granulation. A variety of upstream and downstream equipment is available. Services include a process NJ development laboratory and ongoing training/workshops.
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UPCOMING WEBCASTS

Replacing Settle Plates with Active Air Sampling
Wednesday, November 13, 2019 at 10am EST | 9am CST | 3pm GMT | 4pm CET
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How to Approach Preparative LC for Compound Purification in the Research and Development Laboratory
Thursday, November 7, 2019 at 11am EST | 8am PST | 4pm GMT | 5pm CET
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Choosing The Right CDMO For Late-Phase Clinical Trials
Wednesday, October 30, 2019 at 10am EST | 9am CST | 3pm GMT | 4pm CET
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New Research Revealed on a Promising Functional Alternative to Surfactants within Biologic Formulations
Tuesday October 29, 2019 at 10am EDT | 9am CDT | 2pm GMT | 3pm CET
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Data Integrity and the Next Level of Connectivity in a Modern Lab
Tuesday, October 29, 2019 at 11am EDT | 8am PDT| 3pm GMT| 4pm CET
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A Roadmap for Early Development to Commercial Manufacturing
Thursday, October 24, 2019 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST
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An Integrated Approach to Rapidly Delivering Bioavailability-Challenged Small Molecules to the Clinic
Wednesday, October 23, 2019 at 11am EDT| 8am PDT|4pm BST|5pm CEST
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New Draft USP <922> Chapter for Water Activity Measurement
Tuesday, October 22, 2019 at 11am EDT| 8am PDT| 4pm BST | 5pm CEST
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Workflow Breakthroughs that Are Improving Data Quality and Efficiency and Changing Pharmaceutical Analysis
Europe: Wednesday, October 16, 2019 at 9am EDT | 2pm BST | 3pm CEST
US: Wednesday, October 16, 2019 at 2pm EDT | 1pm CDT| 11am PDT
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ON DEMAND WEBCASTS

APIs and ADCs: A Journey Through High Potency
On Demand
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Excipient Engineering and Design to Enable Continuous Manufacturing
On Demand
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How Can You Transform the Patient Experience through Digital Transformation?
On Demand
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The Evolution of Cellulose in Tableting Technology
On Demand
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The Product Development Superhighway: Leveraging End-to-End Solutions for Market Success
On Demand
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Protecting Oxygen-Sensitive Formulations Throughout the Product Lifecycle
On Demand
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From Basics to Best Practices: Exploring Bioassays and Binding Assays
On Demand
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Identifying and Solving Scale-up Challenges in the Synthesis and Formulation of Small-Molecule APIs
On Demand
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Leveraging Sustainable Sourcing Practices
On Demand
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EVENTS

ISPE Annual Meeting

Oct. 27–30, 2019 | Las Vegas, NV


CPhI Worldwide

Nov. 5–7, 2019 | Frankfurt, Germany


more events

eBOOK

Biologics and Sterile Drug Manufacturing 2019 eBook

The editors explore novel technologies for the formulation, manufacture, purification, and delivery of sterile small- and large-molecule drugs including single-use systems, facilities and equipment, contamination issues, and process analytics.


download the eBook
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