Build your pharma development and manufacturing knowledge base with the latest whitepapers, application notes, posters, and other educational resources from bio/pharma industry suppliers.

Detecting Small Amounts of Multiple API Polymorphic Forms in Powder Blends

Renishaw

The stability, bioavailability, and processability of an active pharmaceutical ingredient (API) are key to a candidate molecule’s ability to be developed into a commercially viable product.

Analysis Using Counter-Rotating Twin Screw Extruder

Brian Machado, Abbe Haser, Feng Haight, Charlie Martin, and Augie Zhang; Leistritz Extrusion

Various extrusion operating conditions and formulations were used to enhance the solubility and recovery of meloxicam (MLX) in copovidone to near 100% on a counter-rotating twin screw extruder (TSE).

Safety & Flexibility: Flow Chemistry

Peter Pöchlauer; Thermo Fisher Scientific

Download this whitepaper to learn how to evaluate whether your API will perform better with batch versus flow chemistry, as this dictates not only the process you will use for scale-up but also the facility and expertise needed to do it successful.

Advanced HDX-MS and Native-MS for Improved Biologic Candidate Selection and Development

Jennifer S. Chadwick, PhD, Kirtland Poss, MBA, and Shiaw-Lin Wu, PhD; BioAnalytix

Potential for improving identification of successful biologic drugs and de-risking CMC and clinical designs earlier through strategic application of advanced mass spectrometry (MS), specifically by assessing target engagement using hydrogen deuterium exchange (HDX) and native MS analyses to guide biologic development decisions, is discussed.

Rapid & Precise Moisture Analysis for Healthcare Products

Ian Olmsted, PhD; CEM

One of the critical parameters in pharmaceutical manufacturing is moisture content. The SMART Q uses patented and proprietary technology to bring moisture test times down significantly without compromising accuracy or precision.

The Hidden Problems with Relaundering Microfiber Mops

Contec, Inc.

There are notable risks associated with using relaunderable mops in a cleanroom environment. Yet, some continue to do so. In this whitepaper, learn how and why you should employ single-use products to improve facility cleanliness.

Applications in Pharmaceutical Manufacturing

Alconox, Inc.

The use of aqueous cleaning in pharmaceutical manufacturing can provide numerous benefits in terms of effectiveness, minimal surface residue, and easier cleaning validation.

Pipelines and Patients Drive Finished Dosage Opportunities

CPhI North America

With fewer compounds available, drug developers are using compounds with good therapeutic effects despite bioavailability challenges for patients to dose less frequently and reduce complexity as a major selling point.