LCGC Europe Weekly Update
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LCGC Europe
3 October, 2019
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LCGC Blog

Automated Dynamic Liquid-Liquid Microextraction (DLLME) – Improve Sample Extraction, Buy Some Time, and Reduce Environmental Footprint

The improved performance of chromatographic detectors, most notably mass spectrometers, has enabled many advances in analytical science, however, one such advance may be given less prominence than perhaps it should.
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Features

Clinical Metabolomics: Expanding The Metabolome Coverage Using Advanced Analytical Techniques

This review discusses the novel separation and detection strategies that are considered promising in clinical metabolomics to enhance the metabolome coverage. It includes HILIC, SFC, multidimensional LC approaches, as well as IMS and the data-independent SWATH-MS acquisition. Read more


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Advances in Chromatography for Macromolecule Analysis
An online resource with useful tools and practical information for separation scientists who want to find out more about Macromolecule Analysis. The site provides useful webcasts, videos, application notes, ebooks, and more from leading practitioners in the field of chromatography.
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mORE Features

The 9th International Symposium on Recent Advances in Food Analysis (RAFA 2019)

The 9th International Symposium on Recent Advances in Food Analysis (RAFA 2019) will take place in Prague, Czech Republic, on 5–8 November 2019. This preview offers a glimpse of what to expect at the conference. Read more

News

New LC–MS Detection Method for Short Peptides

Researchers from the University of Rome have developed a strategy for the identification of underivatized short peptides in urine using graphitized carbon black (GCB) solid-phase extraction (SPE) and liquid chromatography–mass spectrometry (LC–MS). Read more


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Micro Pillar Array Column Technology Resource Center
An online resource with useful tools and practical information for separation scientists who want to find out more about how micro-pillar array columns can benefit the laboratory scientist in practice. The site provides useful technical notes, video interviews, and executive summaries of cutting-edge applications from leading practitioners in the field of proteomics and biopharmaceutical applications.
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Application Notes

Fast and Easy Injection of Large Sample Volumes in Preparative HPLC

The 1290 Infinity II Preparative Binary Pump is far more than just a gradient pump. An integrated solvent valve enables high-speed injections directly onto the column. / Read More /

Automated Metabolic Stability Assays

Automated metabolic stability assays with sample incubation and LC-MS/MS determination are presented for use in drug metabolism and pharmacokinetic (DMPK) laboratories./ Read More /


FEATURED PRODUCTS

Agilent 6495C Triple Quadrupole LC/MS system

The highest performance LC/TQ available with Agilent's third generation iFunnel design, ideally suited for peptide quant as well as multiresidue applications that require ppt sensitivity. The combination of utmost sensitivity, extended mass range, ease of maintenance with VacShield technology, and the power and flexibility of MassHunter makes this the system of choice for demanding applications./ Learn More /

Polymeric Achiral Phases

Daicel introduces three new polymeric phases for use in achiral separations. These phases combine polymeric robustness with unique chemical composition to ensure new and reliable separations. DCpak P4VP, PBT, and PTZ. / Learn More /

Automated Sample Clean-up Solutions

Whether PFAS, pesticide or mycotoxin analysis – the robust and cost-effective clean-up system FREESTYLE overcomes every challenge, even fully automated from extract to chromatogram. Convince yourself: RAFA 2019 (Prague), booth 15. /Learn more/

Industry-standard sampling tubes

Thermal desorption tubes from Markes are manufactured to the highest quality, delivering optimum results time after time. Suitable for all TD applications, including environmental air monitoring, fragrance analysis, and breath monitoring. / Learn More /

Entris® II — Best Value in its Class

Entris® II from Sartorius is the only balance in its class featuring isoCAL, LED touch technology and 12 built in applications. Backed by almost 150 years of German engineering expertise, and available in 40 different models, you’ll easily find an Entris® II balance that exactly meets your specific weighing needs. / Learn More /

Backpressure regulation up to 300bar

As an extension to the VICI Jour® Back Pressure Regulators the new JR-BPR3 offers an extended application range. Pressures from 90-300bar (1300-4200psi) are easily manual adjustable. / Learn More /


UPCOMING WEBCASTS

Analyse Multi-Attributs des Anticorps Monoclonaux par LC-2D et la Spectrométrie de Masse Haute Résolution

Jeudi, 3 octobre 2019, 2:00pm CEST
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Digging Deeper in Every Direction: Developing a Next-Generation Platform for High-Throughput Multi-Faceted Protein Characterization

Thursday, Oct. 3, 2019 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST
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Current and Future Technologies to Assist in Compliance and Computer Validation for GxP Systems

Thursday, Oct. 3, 2019 at 10am EDT | 9am CDT | 3pm BST | 4pm CEST
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Rapid Low-level Identification and Quantitation of Host Cell Proteins

Thursday, Oct. 10, 2019 at 2pm BST | 3pm CEST | 2pm EDT | 1pm CDT | 11am PDT
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Chromatographic Method Development for Antibody-Drug Conjugates

Tuesday, Oct. 15, 2019 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST
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Acquiring Laboratory Equipment: Payment Plan Options vs. Large Upfront Capital Investments

Monday, Oct. 21, 2019 at 9am EDT | 2pm BST | 3pm CEST | 2pm EDT | 1pm CDT | 11am PDT
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Garantire la compliance e l’integrità dei dati: servizi Agilent CrossLab Enterprise per la conformità del tuo laboratorio

Mercoledì, 23 ottobre 2019 alle ore 14 CEST
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Maximizing Throughput and Metabolome Coverage with Dual Separation LC-MS for Improved Bioprocessing Outcomes

Wednesday, Oct. 23, 2019 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST
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HPLC Detectors - What, Where, When, and How

Thursday, Oct. 24, 2019 at 11am EDT| 8am PDT| 4pm BST| 5pm CEST
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Applications of Field-Flow Fractionation

Tuesday, Oct. 29, 2019 at 11am EDT | 8am PDT | 3pm GMT | 4pm CET
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ON DEMAND WEBCASTS

Expanded Capabilities for Bioanalysis Leveraging a Chromatography Data System Streamline Your LC-MS Workflows


Unlock the Full Potential of Your Lab


Understanding and Overcoming Separation Challenges in the Biological Drug Development Process


Regulatorische Erkenntnisse und Compliance-Trends


Rapid Volatile Impurity Analysis in Pharmaceutical Products Using SIFT-MS


Developing a Robust CQA Monitoring Method via Multi-Attribute Monitoring Principles for Therapeutic Monoclonal Antibody Development, Manufacturing, and Lifecycle Management


 

Understanding Biotherapeutic Product Quality Attributes through a Multi-Attribute Method (MAM) Lab-of-the-Future


Ion Chromatography: Modern Ways to Increase Productivity to Get the Most out of Your Ion Analysis


Multi-Class Pesticide Quantitation with a Comprehensive Workflow


Simplifying Solid Phase Extraction for Faster and Cleaner Results


Keeping Pace in a Busy Environmental Lab by Leveraging Emerging Analytical Techniques


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