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Thank you for your continued interest in LCGC's content series on How to Troubleshoot HPLC Extra Peaks and Contamination Like a Pro.

If you'd like to learn more about this topic, the following white paper may be of interest to you.


Avoid Ghost Peaks in HPLC, GC and MS Chromatograms

Chemical compounds can leach from common laboratory equipment during sample storage and sample preparation. These compounds can introduce unwanted ghost peaks in HPLC, GC and MS and interfere with sample analysis in a range of activities including analytical quality control. Extraction samples from Sartorius Optifit and Safetyspace® filter tips and their low retention variants were tested for leachables using HPLC, GC-MS and LC-MS. These pipette tips were found to be practically free of leaching compounds and are therefore suitable for use in highly sensitive analytical methods such as HPLC, GC and MS.

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