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In our January issue:
COLUMNS:
LC TROUBLESHOOTING
The Effect of Buffer Capacity in LC
What concentration of aqueous buffer should I use in the mobile phase when developing a reversed-phase LC method for the analysis of ionogenic compounds?
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GC CONNECTIONS
Thirty-Two Years of GC
In his last “GC Connections” article before stepping away from the role of Editor, John Hinshaw gives some perspective on how GC has changed and grown over the years, and where it might go in the future. Read more >>
SAMPLE PREPARATION PERSPECTIVES
Sample Preparation Goes Subzero
A new technique, ice concentration linked with extractive stirrer (ICECLES), provides highly efficient isolation of trace compounds from aqueous samples. ICECLES combines freeze concentration with stir-bar sorptive extraction into a seamless analytical extraction methodology. This month, we discuss how to perform this relatively simple technique, and discuss its advantages and limitations. Read more >>
COLUMN WATCH
Making the Most of Size-Exclusion Bioseparations Using Sub-2-μm Column Technology
With SEC, special care is required to achieve in practice the chromatographic efficiency that is expected from theory. Read more >>
FEATURES:
Pittcon 2020: Chicago Bound
A look at what’s in store for chromatographers at Pittcon 2020, which takes place in Chicago, Illinois, USA, from 1–5 March 2020.

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PEER-REVIEWED ARTICLE:
Quantifying Phytocannabinoids
A simple UHPLC−HRMS/MS method for the determination of seventeen phytocannabinoids has been developed and validated for Cannabis plants, extracts, and oils.

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